At My Flow MD, we follow a careful “start low, go slow” approach to ensure safety and maximize results. Retatrutide is a potent triple-action GLP-1, GIP, and glucagon receptor peptide, so gradual dosing is essential for tolerance and sustained success.

Begin at the lowest dose once weekly and remain there for at least four consecutive weeks. Only increase the dose if you experience no side effects such as nausea, bloating, or fatigue. Each increase should be small and physician-guided.

If side effects occur, pause or lower the dose until fully resolved before any change. This slow, steady titration allows your metabolism to adapt, minimizes GI symptoms, and promotes long-term fat loss, improved focus, and balanced energy.

Retatrutide works best when introduced with patience. This minimizes risks of side effects and helps your body find its natural flow.

WeeksWeekly DoseNotes
Weeks 1-41 mginitial low dose to assess tolerance
Weeks 5-82 mgif tolerated OK to increase
Weeks 9-124 mgfurther ramping
Weeks 12+6 mg escalation in 2-mg steps, every four weeks. Max dose 12mg weekly.